Pneumonia. Ventilator associated pneumonia
Conditions
Interventions
Intervention 1: Intervention group: Patients who undergo invasive ventilation for more than 3 days are randomly divided into two groups: Intervention group: amikacin powder without sulfite (Caspian Ph
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age 18 and above Absence of lung disease and lung mass No use of chemotherapy drugs Absence of intestinal nutrition No receiving of Antibiotics before the onset of VAP Absence of kidney disease and chronic kidney failure with basic glomerular filtration less than 30 ml in minutes No removing the patient's tracheal tube within the next 48 hours after insertion Lack of sensitivity to amikacin Absence of Myasthenia gravis Not pregnant or Lactating Absence of covid-19 disease (negative PCR) GFR more than 50
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early and late onset pneumonia. Timepoint: 14 days from beginning. Method of measurement: CPIS checklist.;Mortality. Timepoint: 14 days. Method of measurement: Checklist.;Ventilator time. Timepoint: 14 days. Method of measurement: Checklist.;ICU hospitalisation. Timepoint: 14 days. Method of measurement: Checklist.;Glomerular filtration rate. Timepoint: Every day for 14 days. Method of measurement: GFR formula. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Ourang
Arak University of Medical Sciences
Outcome results
None listed