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The effect of tadalafil on spinal cord injury patients

Evaluation of Tadalafil Effects on Function of Detrusor Muscle in Hypo-contractile Bladder of Patients Suffering From Spinal Cord Injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220623055260N1
Enrollment
12
Registered
2022-07-08
Start date
2022-09-23
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Flaccid neuropathic bladder. Flaccid neuropathic bladder, not elsewhere classified

Interventions

Intervention group: for 3 months, Tadalafil 5 mg from Hashtgerd Pharmaceutical Company's Prucial brand in the amount of 45 pills is given to them every other night (this pill from Hashtgerd's Prucial

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: All male patients between the ages of 18-55 years old Suffering from hypocontractile neurogenic bladder as a result of spinal cord trauma At least 6 months passed from spinal cord trauma Having hypocontractile bladder in the Urodynamic testing

Exclusion criteria

Exclusion criteria: lack of informed consent History of sensitivity to phosphodiesterase 5 inhibitors History of taking drugs containing nitrate compounds Heart problems History of priapism

Design outcomes

Primary

MeasureTime frame
Bladder contraction index (BCI). Timepoint: Before of beginning of the intervention and 3 or 6 months after the starting intervention. Method of measurement: urodynamic study.;Volume factor of excreted urine. Timepoint: Before of beginning of the intervention and 3 or 6 months after the starting intervention. Method of measurement: urodynamic study.;Urinary residue. Timepoint: Before of beginning of the intervention and 3 or 6 months after the starting intervention. Method of measurement: urodynamic study.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ghorbani

Mashhad University of Medical Sciences

GhorbaniMH951@mums.ac.ir+98 51 3462 6165

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026