Evaluation of the effectiveness of neurofacial prolotherapy dextrose ontemporomandibular joint disorders

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220620055227N1

Enrollment

Registered

2022-09-03

Start date

2022-09-23

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular joint pain.

Interventions

Intervention 1: Intervention group: The intended study will be conducted in patients referred to Imam Reza (AS) Hospital. The patients are divided into two intervention and control groups. In the prol

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: All patients with temporomandibular joint disorders Informed consent of the patient and willingness to participate in the study

Exclusion criteria

Exclusion criteria: Active infection in the temporomandibular joint Pregnancy and breastfeeding History of surgery in the joint itself A history of fracture or dislocation in the temporomandibular joint History of tumor and malignancy in place Coagulation disorders Use of systemic corticosteroid drugs in the last month diabetes Systemic rheumatological disorders Taking anticoagulant drugs

Design outcomes

Primary

Measure	Time frame
Pain intensity based on visual analog scale after intervention. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month, then 3 and 6 months after the intervention. Method of measurement: Visual analog scale (VAS) questionnaire.;Severity of functional impairment based on visual analog scale after intervention. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month, then 3 and 6 months after the intervention. Method of measurement: Visual analog scale (VAS) questionnaire.;The maximum distance between teethUpper and lower bite that can be done by the patientIt can be done without causing pain, after the intervention.Community Verified icon. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month, then 3 and 6 months after the intervention. Method of measurement: Ruler in mm.;Additional sound found during opening and closing of the mouth in the temporomandibular joint. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month, then 3 and 6 months after the intervention. Method of measurement: During the doctor's examination.	—

Measure

Time frame

Pain intensity based on visual analog scale after intervention. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month, then 3 and 6 months after the intervention. Method of measurement: Visual analog scale (VAS) questionnaire.;Severity of functional impairment based on visual analog scale after intervention. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month, then 3 and 6 months after the intervention. Method of measurement: Visual analog scale (VAS) questionnaire.;The maximum distance between teethUpper and lower bite that can be done by the patientIt can be done without causing pain, after the intervention.Community Verified icon. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month, then 3 and 6 months after the intervention. Method of measurement: Ruler in mm.;Additional sound found during opening and closing of the mouth in the temporomandibular joint. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month, then 3 and 6 months after the intervention. Method of measurement: During the doctor's examination.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSepanta Hatam

Artesh University of Medical Sciences

sepanta3v@yahoo.com+98 21 8609 6350

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026