Patients with gastroesophageal reflux. Gastro-esophageal reflux disease
Conditions
Interventions
Intervention 1: Intervention group 1: Zenian essential oil capsules 150 mg: They use it once a day for 4 weeks. Zenian essential oil is produced in Kashan essential oil Barich pharmaceutical company.
Sponsors
Yasouj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Being 18-60 years old Consent to participate in the study and sign the informed consent form Diagnosing gastroesophageal reflux by gastroenterologist based on ROME lll criteria Body mass index (BMI) less than 30 (BMI>30) Absence of systemic diseases Absence of neurological defects
Exclusion criteria
Exclusion criteria: Taking antibiotics or non-steroidal anti-inflammatory drugs 2 weeks before the study Previous participation in studies similar to the current research Drug or alcohol abuse Existence of gastrointestinal malignancy based on history, physical examination, laboratory tests (for example, the number of white blood cells, CRP, ESR, and upper endoscopy) Liver and kidney function disorders based on laboratory tests Pregnancy History of severe allergy to medicinal plants History of upper gastrointestinal surgery and serious diseases such as heart failure, diabetes, epilepsy, previous or current significant psychiatric disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reflux Symptom Index. Timepoint: Before and after the intervention. Method of measurement: reflux symptom index questionnaire.;Health-related quality of life - gastroesophageal reflux disease (GERD-HRQL. Timepoint: Before and after the intervention. Method of measurement: Health-related quality of life - gastroesophageal reflux disease (GERD-HRQL). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEhsan Elahinia
Yasouj University of Medical Sciences
Outcome results
None listed