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Evaluation of Brassica oleracea and Zingiber officinale Gel in Knee Osteoarthritis

Formulation and Evaluation of Brassica oleracea and Zingiber officinale Gel in Knee Osteoarthritis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220615055179N4
Enrollment
375
Registered
2024-12-27
Start date
2025-01-12
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis. Unilateral primary osteoarthritis, unspecified knee

Interventions

Sponsors

Muhammad Nawaz Sharif University of Agriculture
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: According to the Kellgren and Lawrence system of grading, patients with the grade 1-2 knee osteoarthritis Both gender Age 40-70 years

Exclusion criteria

Exclusion criteria: Neural defects Injected with steroidal injections in the past 2 years Rheumatoid arthritis Total knee replacement Tumors in the area of treatment The patients who are not co-operative during the study Fractures or any other orthopedic condition in the treatment limb

Design outcomes

Primary

MeasureTime frame
Inflammation. Timepoint: Pre (before starting the intervention) and Post evaluation (after 3-4 weeks when treatment sessions/ intervention will be completed depending on different individuals and conditions or grades of different individuals). Method of measurement: C-reactive protein (CRP), Interleukin-6, and Erythrocyte Sedimentation Rate (ESR).;Pain. Timepoint: Pre (before starting the intervention) and Post evaluation (daily after each treatment session, evaluation will be done). Method of measurement: Visual Analog Scale (VAS),Numerical Pain Rating Scale (NPRS), and Pain Catastrophizing Scale (PCS).

Secondary

MeasureTime frame
Stiffness, Pain and Activity of daily living. Timepoint: Pre (before starting the intervention) and Post evaluation (after every 3rd session of treatment, evaluation will be done). Method of measurement: Western Ontario and McMaster Universities Arthritis Index (WOMAC) scale.;Knee joint range of motion. Timepoint: Pre (before starting the intervention) and Post evaluation (after every 3rd session of treatment, evaluation will be done). Method of measurement: Goniometry.

Countries

Pakistan

Contacts

Public ContactQurat-Ul- Ain

Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan

qain0635@gmail.com+92 303 9427506

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026