Formulation of Polyherbal Gel and Evaluation of Anti-nociceptive and Anti-inflammatory Activities

Formulation of Polyherbal Gel and its Evaluation for Anti-nociceptive and Anti-inflammatory Activities in Sports Injuries with superficial massage and phonophoresis in comparison with diclofenac

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220615055179N1

Enrollment

200

Registered

2023-01-14

Start date

2022-03-11

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscular injuries. Primary disorders of muscles

Interventions

Intervention 1: Intervention group-1: The first group received topical application of polyherbal gel, formulated from aqueous-methanolic (30:70) extracts Cinnamomum verum (2.8%), Curcuma longa (2.8%),

Eligibility

Sex/Gender

All

Age

16 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1st and 2nd grade soft tissue injuries 16-70 years Both gender

Exclusion criteria

Exclusion criteria: Any type of allergy from the ingredients used for polyherbal gel formulation Skin problem Cancer Diabetic peripheral neuropathy Other neurological disorders Any type of bone fractures Open injuries Patients with casts Patients with splints

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: pre and post evaluation. Method of measurement: Numeric pain rating scale (NPRS).	—

Secondary

Measure	Time frame
Activities of daily living. Timepoint: Pre and post evaluation. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale.;Stiffness. Timepoint: Pre and post evaluation. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale.	—

Countries

Pakistan

Contacts

Public ContactImran Ahmad Khan

Muhammad Nawaz Sharif University of Agriculture

imranahmadkhandurrani@gmail.com+92 333 6120602

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026