Sepsis. Other sepsis
Conditions
Interventions
Intervention 1: Intervention group: 64 patients who, after assessing the severity of sepsis using the SOFA criteria, will undergo a structured training program to educate caregivers about essential as
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Aged between 18 and 60 years GCS between 4 to 11 Absence of any underlying heart, respiratory, diabetes, or immune system deficiency disease Not be under treatment with any injectable or oral antibiotics at the time of study entry The patient has a tracheostomy and is connected to supplemental oxygen via a T-piece Not under mechanical ventilation No history of alcohol or drug abuse The patient should be fed via NG or OG Tube The patient should not have any symptoms of sepsis or inflammatory disease upon entry into the study, as confirmed and diagnosed by relevant physicians The patient and family have no history of receiving formal education on sepsis prevention or participating in similar interventions The patient's family must be fluent in Persian The body mass index (BMI) between 18 to 30 The duration of hospitalization in the intensive care unit is between 20 to 40 days The patient's initial hospitalization was not due to infectious, inflammatory, or systemic disease The family must be able to provide care at home and there must be at least one designated caregiver Less than two weeks have passed since the patient was discharged and began home care
Exclusion criteria
Exclusion criteria: Have a history of CPR during hospitalization Be undergoing dialysis treatment Patient with a grade 2 or higher pressure ulcer The patient becomes unwell during the study and requires ventilator support or re-hospitalization Being on intravenous nutrition Acute sepsis during the study Failure of the family to continue follow-up or withdrawal from the intervention Emergence of a new infection in the patient during the study, such as urinary or respiratory infection If the patient's family decides to provide palliative care during the study Death of the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sepsis score based on SOFA scale. Timepoint: Assessing the sepsis at the beginning of the study and after the intervention. Method of measurement: The sequential organ failure (SOFA) score is used to assess sepsis. This scale is a measure for assessing vital organ failure in patients with sepsis and determining the severity of the disease. The SOFA score is particularly useful in diagnosing and predicting mortality in sepsis patients and is recommended in the Surviving Sepsis Campaign guidelines. This score includes assessing the function of six vital organs as follows: respiratory (PaCo2/FiO2) - cardiovascular (mean arterial pressure) - hepatic (bilirubin) - coagulation (platelets) - renal (creatinine and urine volume) - nervous system (GCS). Each component of this score has a scoring range between 0 and 4, and the total score range is between 0 and 24. The interpretation of the results is as follows: Scores of 0 to 6 indicate normal organ function or mild damage / Scores of 7 to 12 indicate moderate dysfunction / Scores of 13 to 24 indicate vital organ failure and high risk of mortality. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sepsis. Timepoint: At first and after the intervention. Method of measurement: SOFA score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAtena Shojaie
Kerman University of Medical Sciences
Outcome results
None listed