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Evaluation the effect of different dosages of prophylactic phenylephrine infusion effect on hypotension during surgery

Comparing the different dosages of prophylactic phenylephrine infusion effect on hypotension in elderly patients under spinal anesthesia in orthopedic surgeries

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220612055143N1
Enrollment
60
Registered
2022-06-18
Start date
2022-06-22
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blood pressure during surgery. Hypotension due to drugs

Interventions

Intervention 1: Intervention group: Phenylephrine, manufactured by BB Pharma, will be injected intravenously in 10 cc syringes containing 10 mg / ml in 100 ml of normal saline immediately after changi

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 60 years American Society of Anesthesiologists physical status classification I and II Patients under spinal anesthesia

Exclusion criteria

Exclusion criteria: Heart rate less than 45 Drug sensitivity to local anesthetics Existence of uncontrolled systemic diseases such as diabetes or high blood pressure Heart disease such as heart failure or arrhythmias History of neurological or psychological diseases Existence of any contraindications to performing spinal anesthesia

Design outcomes

Primary

MeasureTime frame
Mean blood pressure. Timepoint: In the first 10 minutes every minute and then every 5 minutes until the end of the operation. Method of measurement: None invasive blood pressure.;Mean Pulse rate. Timepoint: In the first 10 minutes every minute and then every 5 minutes until the end of the operation. Method of measurement: Electrocardiogram.

Secondary

MeasureTime frame
Nausea and vomiting. Timepoint: During operation. Method of measurement: patient observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMitra Golmohammadi

Oroumia University of Medical Sciences

mitragolmohammadi@yahoo.com+98 44 3223 4897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026