Evaluating the effect of intraperitoneal injection of ondansetron during elective caesarean section on postoperative pain intensity after caesarean section

Investigating the effect of intraperitoneal injection of ondansetron during elective caesarean section on postoperative pain intensity in pregnant mothers undergoing the first repeated caesarean section In kamali hospital: A clinical trial study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220610055121N1

Enrollment

Registered

2022-09-12

Start date

2022-10-22

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Examining the pain level of pregnant mothers after cesarean section.

Interventions

Intervention 1: Intervention group: Ondansetron 8 mg ampoule (Exir,Iran) with 16 cc of normal saline (Total 20 cc) is poured intraperitoneally into the abdominal cavity before closing the peritoneum.

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: A candidate for cesarean delivery due to a previous cesarean section Having a history of cesarean delivery healthy fetus ASA II Age between 20-40 years gestational age of term

Exclusion criteria

Exclusion criteria: Having an underlying disease Emergency cesarean section History of ondansetron allergy Receiving painkillers or sedatives 24 hours before surgery

Design outcomes

Primary

Measure	Time frame
Pain score. Timepoint: 0, 0.5, 1, 1.5, 3, 6 hours after the surgery. Method of measurement: Visual analogue scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFerdos Zamani Khalili

Karaj University of Medical Sciences

f.zamani3130@gmail.com+98 26 3226 6851

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026