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The effect of dienogest, Oral contraceptive pill(OCP), Decapeptyl treatment, and fresh transfer method on pregnancy outcomes in women with endometriosis

The effect of dienogest, Oral contraceptive pill(OCP), Decapeptyl treatment, and fresh transfer method after ovum pickup in IVF women candidates on pregnancy outcomes in women with endometriosis

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220609055118N1
Enrollment
88
Registered
2022-08-30
Start date
2022-09-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis. Endometriosis

Interventions

Intervention 1: The first intervention group: Patients in this group were treated with dienogest at the rate of 2 mg/kg for 3 months, and then IVF was immediately performed on them. Intervention 2: Th
So that they receive a dose of medicine every 28 days. Then 15 days after the last dose, IVF is performed on them. Intervention 4: Fourth intervention group: For patients in this group, without receiv

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 45 Years

Inclusion criteria

Inclusion criteria: Infertile women Reproductive age 30-45 years Suffering from any of the stages 3 or 4 of endometriosis IVF candidate Consent to participate in the study

Exclusion criteria

Exclusion criteria: Any drug sensitivity History of thromboembolic diseases, malignancy Positive family history for thrombophilia Contraindication of contraceptive use, GnRH agonist Prohibition of pregnancy Having infectious diseases such as hepatitis B, C or HIV

Design outcomes

Primary

MeasureTime frame
Level of human chorionic gonadotropin (B-HCG). Timepoint: After the intervention. Method of measurement: Urinalysis.;Endometrial thickness. Timepoint: Before and after the intervention. Method of measurement: Sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHatav Ghasemi Tehrani

Esfahan University of Medical Sciences

tehrani@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026