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"Effect of vitamin D on anxiety and depresion of patients with colorectal cancer"

Evaluation of the effect of serum vitamin D levels on anxiety and depression in patients with colorectal adenocarcinoma

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220609055113N1
Enrollment
45
Registered
2022-09-04
Start date
2023-03-08
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Anxiety. Condition 2: Depression. Anxiety disorder, unspecified Major depressive disorder, single episode, unspecified

Interventions

Intervention 1: The first intervention group: patients with a serum level of 25-hydroxyvitamin D3 less than 12 ng/ml receive 8 pearls of 50000 units of cholecalciferol from Zahravi Pharmaceutical Comp

Sponsors

Islamic Azad University
Lead Sponsor
Zahravi Pharmaceutical Company
Collaborator
Reza Radiotherapy and Oncology Center
Collaborator
Omid parsina damavand pharmaceuitical company
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Ability to read and write in Persian Ability to answer questionnaire questions

Exclusion criteria

Exclusion criteria: Complicated diabetes or hypertension History of visiting a psychiatrist or psychologist in the last 6 months or taking psychotropic drugs in the last 6 months Pregnancy Breastfeeding Taking vitamin D or vitamin D3 analogs in the last 3 months Vitamin D serum level more than 100 ng/ml

Design outcomes

Primary

MeasureTime frame
Depression score in Zung questionnaire. Timepoint: Before starting intervention, 90 days after starting to take cholecalciferol. Method of measurement: Zung Self-Rating Depression Scale questionnaire.;Anxiety score in Zung questionnaire. Timepoint: Before starting intervention, 90 days after starting to take cholecalciferol. Method of measurement: Zung Self-Rating Depression Scale qestionnaire.;Serum level of 25-hydroxy vitamin D3. Timepoint: Before starting the intervention and 90 days after starting cholecalciferol. Method of measurement: enzyme-linked immunosorbent assay.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhaneh Entezari heravi

Islamic Azad University

r.entezari98@gmail.com+98 51 3765 8488

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026