The effect of hot-tempered diet on the signs and symptoms and levels of thyroid hormones

The effects of hot-tempered diet on signs, symptoms and serum thyroid hormones level in Symptomatic but euthyroid hypothyroid patients treated with levothyroxine.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220608055102N1

Enrollment

Registered

2022-06-13

Start date

2022-07-01

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypothyroidism. Hypothyroidism, unspecified

Interventions

Each person is given dietary measures based on traditional Iranian medicine, which are classified as hot and cold temperament. These recommendations include eliminating cold-tempered foods and consumi

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Hypothyroid patients have been treated with levothyroxine. Patients who have had normal TSH(5-5/0) in the last 3 months. Zulewski score Zulewski score > 3.

Exclusion criteria

Exclusion criteria: Pregnancy. Hypothyroidism caused by surgery or radioactive iodine. Chronic diseases such as diabetes mellitus. Dose changing of levothyroxine during the study. Taking interfering drugs with thyroid tests. Diseases of the hypothalamus and pituitary gland.

Design outcomes

Primary

Measure	Time frame
Zulewski score. Timepoint: At the beginning and 6 weeks later. Method of measurement: Zulewski questionnaire.;Thyroid stimulating hormone serum level. Timepoint: At the beginning and 6 weeks later. Method of measurement: Laboratory.;Triiodothyronine serum level. Timepoint: At the beginning and 6 weeks later. Method of measurement: Laboratory.;Alanine transaminase serum level. Timepoint: At the beginning and 6 weeks later. Method of measurement: Laboratory.;Creatinine serum level. Timepoint: At the beginning and 6 weeks later. Method of measurement: Laboratory.	—

Measure

Time frame

Zulewski score. Timepoint: At the beginning and 6 weeks later. Method of measurement: Zulewski questionnaire.;Thyroid stimulating hormone serum level. Timepoint: At the beginning and 6 weeks later. Method of measurement: Laboratory.;Triiodothyronine serum level. Timepoint: At the beginning and 6 weeks later. Method of measurement: Laboratory.;Alanine transaminase serum level. Timepoint: At the beginning and 6 weeks later. Method of measurement: Laboratory.;Creatinine serum level. Timepoint: At the beginning and 6 weeks later. Method of measurement: Laboratory.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Shirzadi

Esfahan University of Medical Sciences

omid.shirzadi@gmail.com+98 31 3620 1274

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026