The effect of intravenous vitamin C on the incidence of pharyngocutaneous fistula after total laryngectomy

The effect of intravenous vitamin C on the incidence of pharyngocutaneous fistula after total laryngectomy in patients with laryngeal cancer

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220605055077N1

Enrollment

Registered

2022-07-11

Start date

2022-07-23

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laryngeal cancer. Malignant neoplasm of larynx

Interventions

Intervention 1: Intervention group: Vitamin C ampoule of Alborz Daroo company in the amount of 1G by injection intravenous BD or 2 times a day with a volume of 10CC in each turn for 7 days. Interventi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with SCC laryngeal cancer have undergone total laryngectomy and bilateral neck dissection with the same technique.

Exclusion criteria

Exclusion criteria: Diabetes mellitus Preoperative radiotherapy Anemia before surgery Preoperative hypoalbuminemia

Design outcomes

Primary

Measure	Time frame
The incidence of pharyngocutaneous fistula after total laryngectomy. Timepoint: One month after laryngectomy. Method of measurement: Using examination and observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Sanaye Pasand

Tehran University of Medical Sciences

z.sanaye.p@gmail.com+98 21 6670 6106

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026