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The effect of Chicory root extract on radiation therapy-induced dermatitis

The effect of topical use of Chicory root extract gel on the incidence and severity of radiation therapy-induced dermatitis in breast cancer patients.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220601055055N1
Enrollment
44
Registered
2022-07-02
Start date
2022-07-01
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radiodermatitis. Acute radiodermatitis

Interventions

Intervention 1: Intervention group: From the first day of radiation therapy to the end of it (for one month), the intervention group will use 3% chicory root extract gel topically twice a day topicall
They will be used topically in the area under radiation therapy. Tubes of 100 g containing the mentioned gel have been prepared by the Medicinal Plants Research Center of Shahrekord University of Medi

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Tendency to participate in the study Giving informed consent Having breast cancer based on the diagnosis of an oncologist

Exclusion criteria

Exclusion criteria: known allergy to chicory plant and medical contraindication to chicory extract Existence of an ulcerated ulcer or scar at the site of radiation therapy History of previous radiation therapy at the current treatment site History of breast reconstruction (prosthesis) Simultaneous chemotherapy

Design outcomes

Primary

MeasureTime frame
Radiodermatitis score in Radiation Therapy Oncology Group Scale (RTOG Scale). Timepoint: Daily (from the beginning of the study to the end of radiation therapy). Method of measurement: Radiation Therapy Oncology Group Scale (RTOG Scale).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Jafari

Kashan University of Medical Sciences

fatemejafari@yahoo.com+98 31 5554 6633

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026