Migraine headache. G43.0Migraine without aura [common migraine]
Conditions
Interventions
Intervention 1: Intervention group: herbal nasal spray based on oregano- three times a day one puff each nasal orifice. Intervention 2: Control group: placebo nasal spray-three times a day one puff ea
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Migraine based on IHS criteria 2 to 8 migraine attack in a month with less than 15 days headache a month and with at least 48 hours intervals Onset of headaches less than one year ago No warm brain temperament 18 to 65 years old with headache onset no later than 50 years old
Exclusion criteria
Exclusion criteria: Secondary headaches Regular use of antipsychotic or antidepressant drugs during last 3 months for reasons other than migraine Alcohol or drug abuse Drug sensitivity to the drug ingredients Fertile women with no contraception Pregnancy and breast feeding consuming drugs affecting migraine headache or interacting with drug ingredients during last week Analgesic overuse based on IHS criteria Severe physical or psychologic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of migraine headache attacks per month. Timepoint: Three times with one month intervals. Method of measurement: Number of attacks with at least 48 hours of freedom from headache between migraine attacks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Headache severity. Timepoint: Tree times with one month intervals. Method of measurement: Four point verbal scale.;Number and name of analgesics used. Timepoint: Three times with one month intervals. Method of measurement: Recording the name and the number of analgesics used in one month.;Health related quality of life. Timepoint: Three times with one month intervals. Method of measurement: Sf 36 & hit 6 questionaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactJila Naseri
Tehran University of Medical Sciences
Outcome results
None listed