Osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group: Applying Curcumin OG 2% twice a day for 8 weeks on the knee area. Intervention 2: Control group: Applying Curcumin-free OG, twice a day, up to 8 weeks, on the knee
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: Having symptom of pain in joint Osteoarthritis (at Knee), stiffness, difficulty in flexion and extension, swelling for more than 3 months prior to the study Being free of any systemic or dermatological diseases Willing to refrain from using any lotion, gel, balm, moisturizer, cleanser, cosmetic or cream on the treatment areas during the treatment period Being able to give written informed consent in a manner approved by the Institutional Ethics Committee and complying with the requirements of the study Willing to avoid participation in any other interventional clinical trial during current study No known allergy to Curcumin and plants of the ginger family
Exclusion criteria
Exclusion criteria: Showing a systemic or local allergic reaction to Curcumin organogel Discontinuation of the treatment before end of intervention, or stopping it for at least three consecutive days A decision to withdraw from the study Death Hospitalization Moving to another city
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain, Stiffness, Difficulty in knee movement. Timepoint: Before, 1, 2, 4 and 8 weeks after intervention. Method of measurement: The Western Ontario and McMaster Universities Arthritis Index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGholamhossein Yousefi
Shiraz University of Medical Sciences
Outcome results
None listed