Postoperative ileus (POI) is a temporary impairment of bowel motility that commonly occurs after abdominal or colorectal surgery. It delays the return of normal gastrointestinal function, leading to abdominal distension, nausea, vomiting, intolerance to oral intake, and prolonged hospitalization. The study investigates strategies to reduce the duration and severity of postoperative ileus in patients undergoing elective open colorectal surgery..
Conditions
Interventions
Intervention 1: Intervention group: Patients in the intervention group received standard perioperative, intraoperative, and postoperative care according to the ERAS protocol. However, postoperative or
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients aged 18 years or older., Patients scheduled for elective open colorectal surgery. Patients with no pre-existing gastrointestinal motility disorders. Patients with American Society of Anesthesiologists (ASA) physical status classification I–III. Patients able to provide written informed consent
Exclusion criteria
Exclusion criteria: Patients who underwent emergency colorectal surgery (e.g., for bowel obstruction, perforation, or peritonitis). Patients with a history of gastrointestinal motility disorders, such as gastroparesis, irritable bowel syndrome, or chronic constipation. Patients with chronic opioid use for more than two weeks prior to surgery. Patients who had major abdominal surgery within the previous six months. Patients who experienced intraoperative complications requiring deviation from the standard ERAS protocol. Patients requiring postoperative mechanical ventilation for more than 24 hours Patients who were unable to initiate oral feeding within 24 hours after surgery. Patients with cognitive impairments or language barriers that interfered with adherence to the feeding protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resolution of postoperative ileus (POI) was defined as the return of bowel sounds and first passage of gas or stool in the absence of abdominal distension or vomiting. The need for nasogastric tube reinsertion (in cases of vomiting exceeding 100 mL within the first 24 hours) was recorded as an indicator of feeding intolerance and persistence of ileus. Timepoint: Monitoring was performed continuously from recovery until discharge, with key assessment intervals corresponding to the oral feeding protocol at 0–12 hours, 12–24 hours, 24–48 hours, and 48–72 hours postoperatively (reflecting the initiation and progression of oral feeding). The time of first passage of gas or stool, return of bowel sounds, and initiation of the first solid diet were recorded daily until discharge. Method of measurement: Bedside clinical examination: Assessment of bowel sounds and evaluation of abdominal distension.Recording of clinical events by the nurse or clinical team, including the time of first passage of gas or stool, tolerance of oral diet, and the volume of vomiting (for determining the need for nasogastric tube reinsertion).Data extraction from patient medical records and case report forms (CRFs), followed by statistical analysis using SPSS software. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Amir Miratashi Yazdi
Tehran University of Medical Sciences
Outcome results
None listed