Effects of dexmedetomidine and magnesium sulfate in the administration of pituitary surgery anesthesia

A Comparison of Dexmedetomidine and Magnesium Sulfate as an Anesthetic Adjuant in trans-Sphenoid pituitary surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220528055003N1

Enrollment

Registered

2022-07-13

Start date

2022-07-21

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain. Acute pain due to trauma

Interventions

Intervention 1: Intervention group: Thirty patients who are candidates for pituitary surgery transferred to the operating room of Loghman Hakim Hospital (Tehran) will be included in this group randoml

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Candidate for pituitary surgery by trans-sphenoid method Candidate for general anesthesia Satisfaction to participate in the study

Exclusion criteria

Exclusion criteria: Sensitivity to the studied drugs Taking drugs that increase intracranial pressure

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Up to 12 hours after the intervention and once every hour. Method of measurement: Visual Analog Scale.	—

Secondary

Measure	Time frame
Hemodynamic status. Timepoint: From the beginning of the intervention to the end of the intervention (every three minutes). Method of measurement: Monitoring hemodynamic status with the help of cardiopulmonary monitoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNina Pilevar

Shahid Beheshti University of Medical Sciences

Ninapilevar@yahoo.com+98 21 5102 5000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026