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Fluvoxamine in Long COVID

Evaluation of the effect of fluvoxamine in preventing neuropsychiatric symptoms of Long COVID syndrome

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220526054990N1
Enrollment
96
Registered
2022-06-01
Start date
2022-03-01
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Long or Post COVID syndrome. Post COVID-19 condition occurs in individuals with a history of probable or confirmed SARS CoV-2 infection, usually 3 months from the onset of COVID-19 with symptoms and that last for at least 2 months and cannot be explained by an alternative diagnosis.

Interventions

Intervention 1: Intervention group: The drug fluvoxamine maleate 50 mg fc tablet made by Jalinous Pharmaceutical Company, every 12 hours for 10 days, after 4 weeks, patients are contacted and asked a

Sponsors

Artesh University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: Confirmed COVID infection by infectious disease specialist Age over 15 years

Exclusion criteria

Exclusion criteria: History of epilepsy History of mania History of depression Use of other antidepressants Pregnancy and lactationK Kidney dysfunction Liver dysfunction History of cardiac arrhythmia Any drug allergy to fluvoxamine, including skin allergies Severe side effects of fluvoxamine, including malignant neuroleptic syndrome Drug interactions with other drugs consumed by the patient

Design outcomes

Primary

MeasureTime frame
Frequency of any of the neuropsycological symptoms of Long COVID in patients. Timepoint: 4 weeks after COVID symptoms onset. Method of measurement: history taking based on a questionnaire prepared by the researcher.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Ajam

Tehran University of Medical Sciences

a-ajam@alumnus.tums.ac.ir+98 21 8835 6498

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026