Painkiller effect of 4% Lidocaine versus 4% Articaine after wisdom teeth extraction

Comparison of Articaine 4% and Lidocaine 2% for Buccal Infiltration After Inferior Alveolar Nerve Block For Intraoperative Pain Control During Impacted Mandibular Third Molar Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220524054979N1

Enrollment

Registered

2022-07-16

Start date

2022-06-22

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Surgery. Acute pain, not elsewhere classified

Interventions

Intervention 1: Local Anesthesia administration in the mandible with Articaine 4% (SeptocaineFrance, Septodont) (with 1:100000 Epinephrine,3.6 ml, using 27 gauge needle with the speed of 1 mL/min. The

Exir pharmaceutical Co, Iran) (with 1:100000 Epinephrine,3.6 ml, using 27 gauge needle with the speed of 1 mL/min. The needle bevel was at the bone side. Group 1 : Inferior Alveolar nerve Block Anest

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Mandibular Third Molar Surgery Indication

Exclusion criteria

Exclusion criteria: Systemic Disease Analgesics Consumption during last 24 hours Allergic Reaction to Local Anesthesia Agents Hyperalgesic Syndrome Pregnancy and Lactating

Design outcomes

Primary

Measure	Time frame
Postoperative Pain. Timepoint: 7, 4 and 21 days. Method of measurement: Visual Analog Scale.;Anesthesia Duration. Timepoint: 0-12. Method of measurement: Cronometer.;Anesthesia Start. Timepoint: 0-12. Method of measurement: Watch.;Surgery Duration. Timepoint: 0-10. Method of measurement: Cronometer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEhsan Hooshyar

Urmia University of Medical science

Hooshyar.e@umsu.ac.ir+98 44 3336 3600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026