Evaluation of the effect of combined herbal mouthwash (containing Thymus, Myrtus, Glycyrrhiza and Aloe Vera) on the complications of mandibular wisdom tooth surgery

Evaluation of the effect of combined herbal mouthwash (containing Thymus, Myrtus, Glycyrrhiza and Aloe Vera) on postoperation complications of mandibular impacted third molar; A randomized triple-blind clinical trial study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220522054965N1

Enrollment

Registered

2022-08-20

Start date

2022-09-09

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of impacted third molar surgery. Impacted teeth

Interventions

Intervention 1: Intervention group: 280 ml combined herbal mouthwash bottle (containing 1% extract from each four plants: Thymus, Myrtus, Glycyrrhiza and Aloe Vera) - how to use: 10 ml each time - 30

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Willingness and satisfaction of the patient to participate in the study The presence of unilateral or bilateral mandibular wisdom teeth Possessing a panoramic radiograph with high quality and prepared in the last 6 months age between 20-60

Exclusion criteria

Exclusion criteria: Lack of proper cooperation and consent of the patient to participate in the study Suffering from systemic diseases Taking medicine, smoking, alcohol and drugs Pregnancy and breastfeeding in women

Design outcomes

Primary

Measure	Time frame
Swelling. Timepoint: Before and after surgery, the third day, the seventh day, the fourteenth day. Method of measurement: Ruler with millimeter scale.;Trismus. Timepoint: Before and after surgery, the third day, the seventh day, the fourteenth day. Method of measurement: Ruler with millimeter scale.;Pain. Timepoint: Before and after surgery, the third day, the seventh day, the fourteenth day. Method of measurement: Visual Analogue Scale.	—

Measure

Time frame

Swelling. Timepoint: Before and after surgery, the third day, the seventh day, the fourteenth day. Method of measurement: Ruler with millimeter scale.;Trismus. Timepoint: Before and after surgery, the third day, the seventh day, the fourteenth day. Method of measurement: Ruler with millimeter scale.;Pain. Timepoint: Before and after surgery, the third day, the seventh day, the fourteenth day. Method of measurement: Visual Analogue Scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMuhammad Reza Asgari Ghonche

Qazvin University of Medical Sciences

m.asgari77@yahoo.cm+98 28 3369 1527

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026