Ovarian hyper stimulation syndrome. Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: Intervention group: Letrozole 2.5 mg tablet, one every 12 hours from the day of ovulation for 5 days orally, prepared from Abu Raihan Pharmaceutical Company. Intervention 2: Control gr
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
25 Years to 40 Years
Inclusion criteria
Inclusion criteria: Young patients between the ages of 25 and 40 suffer from infertility. Their BMI is between 18 and 35 KG/M2. They have been diagnosed with PCOS according to the Rotterdam criteria. Have at least 15 dominant follicles on the day of trigger administration.
Exclusion criteria
Exclusion criteria: Have a serious medical disease. Have a history of allergy to letrozole. Patients with severe endometriosis. Patients who do not consent to participate in the study. Patients who do not cooperate with the study to return at specific times.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian hyper stimulation syndrome incidence rate. Timepoint: During the first 10 days after ovulation. Method of measurement: Based on the patient's symptoms and determining their severity with the RCOG green-top 2016 guidelines.;Serum estradiol levels. Timepoint: On the day of ovulation, 3 and 6 days after. Method of measurement: Patient's blood sample. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Najjari
Tehran University of Medical Sciences
Outcome results
None listed