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Effect of Letrozole in Medical Abortion

The Effect of 5 days of Letrozole Pretreatment Combined with Misoprostol in Medical Abortion

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220522054961N1
Enrollment
80
Registered
2022-09-28
Start date
2022-10-02
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

medical abortion.

Interventions

Intervention 1: Pregnant women with a gestational age of less than 14 weeks based on last menstural period (LMP) who are candidates for medical abortion and will take 10 mg of Letrozole daily for 5 da

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Any Pregnant Women with Gestational Age Less than 14 Weeks Candidate for Medical Abortion with No Serious Comorbidities No Recent or Recurrent Use of Corticosteroids No History of and Allergy to Letrozol No History of and Allergy to Misoprostol Hemoglobin more than 10 Normal Coagulation and Complete blood count (CBC) test

Exclusion criteria

Exclusion criteria: Recurrent Abortion with Gestational Age Less than 14 weeks

Design outcomes

Primary

MeasureTime frame
Complete Abortion Rate. Timepoint: Trans Vaginal Sonography for Remnant of Production will be Done in Patients Who Dispose of Pregnancy Products. Method of measurement: Complete Disposal of Pregnancy Products before 20 Weeks Gestational Age.;Incomplete Abortion Rate. Timepoint: Trans Vaginal Sonography for Remnant of Production will be Done in Patients Who Dispose of Pregnancy Products. Method of measurement: Incomplete Disposal of Pregnancy Products before 20 Weeks Gestational Age.;Amount of Vaginal Bleeding. Timepoint: 6 Hours Before and 6 Hours After Disposal of Pregnancy Products. Method of measurement: Number of Pads Used in an our.;Surgical Curettage Rate. Timepoint: When Incomplete Abortion Occur after Receiving One Course of Misoprostol based on FIGO Protocol. Method of measurement: The Number of Patients who Underwent Surgical Curettage.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Najjari

Shahid Beheshti University of Medical Sciences

Zahra.z.najjari@gmail.com+98 21 2303 1111

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026