The effect of Tranexamic acid administration on non-traumatic Intracerebral hemorrhage in contrast with placebo

The effect of Tranexamic acid administration on non-traumatic Intracerebral hemorrhage in contrast with placebo in Namazi hospital.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220520054927N1

Enrollment

100

Registered

2022-09-08

Start date

2022-07-23

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraparanchymal hemorrhage. Nontraumatic intracerebral hemorrhage in hemisphere, subcortical

Interventions

Intervention 1: Intervention group: After admission in hospital and diagnosis of intra paranchimal hemorrhage with radiologic evaluations, patients will receive Injection of 1gr tranexamic acid intrav

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age between 18-75 years old Acute non-traumatic intra-paranchimal hemorrhage Less than 12 hours since bleeding

Exclusion criteria

Exclusion criteria: Multiple intra-paranchimal hemorrhage Contraindication for Anti-phybrinolytic treatment Massive ntra-paranchimal hemorrhage (>70cc) Stem ICH cerebral aneurysm or vascular anomalies Post CVA hemorrhagic formation Cerebral venous thrombosis Anti-thrombolytic therapy Brain tumor or infection

Design outcomes

Primary

Measure	Time frame
Expansion of intraparanchymal hemorrhage. Timepoint: Before intervention, 1 and 3 days later. Method of measurement: Brain CT scan.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Jamali

Shiraz University of Medical Sciences

mohammad.jamali.ns@gmail.com+98 71 3647 3882

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026