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Clinical and radiographic effects of a new calcium silicate cement in vital pulp therapy in teeth with close apex

Comparison of clinical and radiographic effects of a new calcium silicate cement with Mineral trioxide Aggregate cement in vital pulp therapy as direct pulp cap in teeth with closed apex

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220519054917N1
Enrollment
90
Registered
2022-06-03
Start date
2022-06-22
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

irreversible pulpitis. Pulp degeneration

Interventions

Intervention 1: Intervention group: Direct pulp cap with MTA cement: After confirming the complete anesthesia of the pulp with a sterile bur, first a large part of caries and weak enamel structures we

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 50 Years

Inclusion criteria

Inclusion criteria: Vital molar teeth (positive response to electrical pulp tester and cold test before treatment and objective observation of pulp bleeding after preparation of access cavity) History of irreversible pulpitis (history of spontaneous or localized pain; irritation due to cold and heat that persists after stimulus removal; pain induced by cold test) or no clinical signs of irreversible pulpitis but with Pulp exposure after removal of caries Patients are in the age range of 12 to 50 years Prepared and able to attend follow-up meetings Patients have signed a consent form

Exclusion criteria

Exclusion criteria: Patients with systemic diseases in which tissue repair is impaired, such as diabetes, cancer, endocrine disorders, AIDS, and those taking corticosteroids. Patients who for any reason can not inject anesthesia containing epinephrine Pregnant or lactating women. Patients with mental and physical disabilities. Patients with poor oral hygiene and periodontal disease in such a way that long-term tooth retention is not possible due to periodontal problems. People like immigrants from other countries who have a great chance of leaving the study. Age of patients less than 12 years (for the treatment of the first molar) and less than 15 years (for the treatment of the second molar) and more than 50 years. Lack of control of pulpal hemorrhage in highly inflamed teeth.(Pulp bleeding can not be controlled by placing a cotton swab dipped in 5.25% sodium hypochlorite in the chamber pulp for a maximum of ten minutes). Teeth that can not be restorated with the usual class one and two restorations with or without cusp reduction. Teeth with localized periodontal disease in a way that the survival of the tooth is not in danger, but due to exposure of the root surface, there is a possibility of pulpal stimulation and disruption of the restoration process. Teeth with external, internal resorption or visible pulp calcifications on periapical radiography Traumatized teeth Teeth with swelling of adjacent soft tissue Teeth with open apex Teeth with pericardial lesion (around the apex or forca area) visible on radiography Taking antibiotics in a recent month Taking painkillers in the last 3 days Existence of defects in restoration in follow-up sessions

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: At intervals of 6, 12, 24 hours and then daily for a week. Method of measurement: Based on the pain recorded on the VAS pain index ruler.;Clinical signs of soft tissue around the roots. Timepoint: 6 months after treatment. Method of measurement: Inflammation, redness, swelling and infection of the soft tissue adjacent to the tooth, spontaneous pain, pain on touch and knock, fistula and abscess.;Symptoms of periapical radiography. Timepoint: Follow-up periods are one week and six months. Method of measurement: It is ranked based on the presence of pdl widening and radiolucency or the absence of any reaction. Existence of internal and external root resorption, apical lesion and canal calcification.;The pulp condition of the treated tooth. Timepoint: Follow-up periods are one week and six months. Method of measurement: It is determined based on EPT and cold tests.;Periapical conditions of the treated tooth. Timepoint: Follow-up periods are one week and six months. Method of measurement: Based on the response to the percusion and touch tests and the radiographic appearance of the desired tooth is determined.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Javad Aslani

Zahedan University of Medical Sciences

Aslani.j1370@gmail.com+98 54 3344 1814

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026