Corona virus (Covid-19). J12.81
Conditions
Interventions
Intervention 1: Intervention group: Patients in the intervention group, in addition to the standard treatment of Covid-19, (dexamethasone at a dose of 6 mg per day and remedSivir at a dose of 200 mg o
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Definitive diagnosis of Covid-19 based on taking a sample from the pharynx and PCR laboratory confirmation Lung involvement more than 50% SPO2 levels below 80% without oxygen or below 88% with oxygen or IL above 10 or ferritin above 1500 Patients who have not responded to other Covid-19 treatments Age over 18 years and consent to participate in the study
Exclusion criteria
Exclusion criteria: History of albumin sensitivity Heparin allergy who cannot receive heparin as an anticoagulant during plasmapheresis Patients with hypocalcemia (citrate used in the plasmapheresis process exacerbates hypocalcemia)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of blood oxygen saturation (SPO2). Timepoint: On days zero (before the intervention), days one, three, five and seven after the intervention. Method of measurement: Pulse oximeter Bitmos Gmbh made in Germany.;Arterial blood oxygen pressure in the analysis of blood gases Pao2. Timepoint: On days zero (before the intervention), days one, three, five and seven after the intervention. Method of measurement: Blood sample to measure blood gases. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospitalization of the patient. Timepoint: End of hospitalization or death of the patient. Method of measurement: By day.;C-reactive protein (CRP) Factor. Timepoint: On days zero (before the intervention), days one, three, five and seven after the intervention. Method of measurement: Blood Test Prestige 24i machine made in Japan. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVajehallah Raeesi
Birjand University of Medical Sciences
Outcome results
None listed