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Investigation of the effect of herbal nasal spray (Iranian Traditional Medicine product) on treatment of allergic rhinitis

The effect of nasal spray based on herbal extracts (traditional Persian medicine product) compared to placebo on the symptoms of patients with allergic rhinitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220517054885N1
Enrollment
76
Registered
2022-10-02
Start date
2022-08-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Rhinitis. Allergic rhinitis, unspecified

Interventions

Intervention 1: Intervention group: receiving herbal nasal spray made by researchers in the pharmaceutical laboratory of the school of Persian and Complementary medicine of Mashhad University of Medic
with the order of 2 puffs every 8 hours inside each nasal cavity for 3 weeks. Intervention 2: Control group: receiving a placebo nasal spray made by researchers in the pharmaceutical laboratory of the

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: All patients 18 years to 70 years old that according to the ARIA guideline and diagnosis of a clinical Immunologist have allergic rhinitis

Exclusion criteria

Exclusion criteria: Diffused Nasal Polyps Pregnancy History of allergy to Coriander or Bitter orange Asthmatic patients Systemic inflammatory diseases Using antihistamines during the last week before the beginning of the study Using inhaled corticosteroids during the last 2 weeks before the beginning of the study

Design outcomes

Primary

MeasureTime frame
Nasal obstruction. Timepoint: Baseline and 3 weeks after intervention. Method of measurement: Total Nasal Symptom Score questionnaire.;Itching/Sneezing. Timepoint: Baseline and 3 weeks after intervention. Method of measurement: Total Nasal Symptom Score questionnaire.;Rhinorrhea. Timepoint: Baseline and 3 weeks after intervention. Method of measurement: Total Nasal Symptom Score questionnaire.

Secondary

MeasureTime frame
Symptom recurrence rate. Timepoint: Baseline and one week after the end of intervention. Method of measurement: Rhinitis Control Assessment Test (RCAT) questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlieh Farabi

Mashhad University of Medical Sciences

farabia971@mums.ac.ir+98 51 3884 8931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026