Comparison of the effect of methadone and morphine on pain after rhinoseptoplasty surgery. Acute Pain
Conditions
Interventions
Intervention 1: Intervention group: n the main and studied group, the desired dose of the drug is 0.15 mg per body weight (ideal weight). Methadone is administered slowly intravenously half an hour af
Sponsors
The University of Qom
Qom Medical Sciences Research Deputy
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Candidate patients for rhinoseptoplasty surgery Normal EKG and (no long QT)
Exclusion criteria
Exclusion criteria: Drug addiction History and psychological illness Patient dissatisfaction History of drug allergy to previous surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain after surgery. Timepoint: The study compares the effect of methadone and morphine on pain after rhinoseptoplasty surgery to measure pain half an hour after surgery and at the end of surgery , patient extubation and recovery 1 and 6 hours after surgery. Method of measurement: In the study "Comparative study of the effect of methadone and morphine on pain after rhinoseptoplasty surgery" is the method of measuring the outcome variable using a clinical information checklist and the second part is the use of a standard pain intensity questionnaire (Visual Analogue Scale) to determine pain intensity in patients. The Visual Analogue Scale (VAS) is a subjective measure of pain. It consists of a 10cm line with two endpoints representing ‘no pain’ and ‘worst pain imaginable’. Patients are asked to rate their pain by placing a mark on the line corresponding to their current level of pain. The distance along the line from the ‘no pain’ marker is then measured with a ruler giving a pain score out of 10.;Hemodynamic variables. (blood pressure, Saturation of Peripheral Oxygen). Timepoint: The study compares the effect of methadone and morphine on pain after rhinoseptoplasty surgery to measure Hemodynamic variables half an hour after surgery and at the end of surgery , patient extubation and recovery 1 and 6 hours after surgery. Method of measurement: Mercury sphygmomanometer.( for the measurement of blood pressure ).Pulse Oximeter (for the measurement of Saturation of Peripheral Oxygen).;Saturation of Peripheral Oxygen. Timepoint: The study compares the effect of methadone and morphine on pain after rhinoseptoplasty surgery to measure (Saturation of Peripheral Oxygen )half an hour after surgery and at the end of surgery , patient extubation and recovery 1 and 6 hours after surgery. Method of measurement: Pulse Oximeter.;Blood pressure. Timepoint: The study compares the effect of methadone and morphine on pain after rhinoseptoplasty surgery to measure (blood pressure ) | — |
Secondary
| Measure | Time frame |
|---|---|
| In the study "Comparative study of the effect of methadone and morphine on pain after rhinoseptoplasty" the secondary outcome could be "hemodynamic changes". Timepoint: The patient hemodynamics are recorded at the end of the operation, patient extubation and recovery and 1 and 6 hours after surgery. Method of measurement: In this study, using the patient's personal and clinical information checklist, including blood pressure and heart rate and blood oxygen saturation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahid Daman Pak Moghaddam
The University of Qom
Outcome results
None listed