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Investigating the effect of Sildenafil topical cream compared to Dexpanthenol cream on neck wound healing

The Evaluation of the Effect of Sildenafil Topical Cream with dexpanthenol on the Healing Process of Scar Caused by Neck Surgeries: A Double Blinded Randomized Controlled Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220516054879N9
Enrollment
46
Registered
2023-11-20
Start date
2023-11-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scar caused by neck surgery. Scar conditions and fibrosis of skin

Interventions

Intervention 1: Intervention group: Receive Sildenafil 5% topical cream three times a day. Intervention 2: Control group: Receiving dexpanthenol 5% topical cream 3 times a day from Pharmachemy pharmac

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: -Patients over 18 years of age who have neck wounds caused by surgery and refer to Amir al-Momenin Hospital in Rasht.- No previous allergy to products containing sildenafil- Not using other drugs that are effective in wound healing- Absence of diseases that interfere with wound healing (chronic systemic diseases of the heart, kidneys, lungs, coagulation disorder, immune deficiency, connective tissue disorder, diabetes, anemia, hemophilia, and malnutrition)- No history of injury or previous surgery and visible lesions in the neck area

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Scar spread. Timepoint: Scar spread will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on the observation of the researcher.

Secondary

MeasureTime frame
Erythema. Timepoint: Erythema will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on the observation of the researcher.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Shahrokhi

Rasht University of Medical Sciences

shahrokhi.mail85@gmail.com+98 13 3336 9019

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026