Bipolar. Bipolar disorder
Conditions
Interventions
Intervention 1: Intervention group: 26 Patients in the intervention group will receive one 600 mg oral n-acetyl cycteine effervescent tablet manufactured by Osve Company, every 12 hours, from 24 hours
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with bipolar disorder older than 18 years Treatment with electroconvulsive therapy
Exclusion criteria
Exclusion criteria: Schizophrenia Drug Abusers Psychiatric diseases with other mental illnesses Bradyarrhythmia Liver or kidney failure History of seizures Drug or alcohol use History of asthma or bronchospasm History of allergy to n-acetyl cycteine Pregnancy Breastfeeding Currently uncontrolled hypertension Active peptic ulcer Receiving nitroglycerin History of severe skin disease such as Steven Johnson
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive impairment. Timepoint: Before intervention and two weeks after beginning of the intervention. Method of measurement: Mini-Mental State Examination questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic blood pressure. Timepoint: Before the intervention and two weeks after beginning of the intervention. Method of measurement: Digital blood pressure measurement device.;Diastolic blood pressure. Timepoint: Before the intervention and two weeks after beginning of the intervention. Method of measurement: Digital blood pressure measurement device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Shahrokhi
Rasht University of Medical Sciences
Outcome results
None listed