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The effects of Hypericum Perforatum and Dexpanthenol topical cream on the healing process of scar

A comparative study of the effects of Hypericum Perforatum and Dexpanthenol topical cream on the healing process of scar caused by neck surgeries

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220516054879N6
Enrollment
48
Registered
2023-07-03
Start date
2023-06-03
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scar caused by neck surgery. Scar conditions and fibrosis of skin

Interventions

Intervention 1: Intervention group: Receiving 3 times a day topical cream formulation of Hypericum perforatum plant with 70% ethanolic extract with 2% concentration of total extract for 3 months. Int

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with neck wounds caused by surgery After removing the stitches obtaining informed consent

Exclusion criteria

Exclusion criteria: Previous sensitivity to products containing Hypericum Perforatom Receiving other drugs effective on wound healing Suffering from diseases that interfere with wound healing (chronic systemic diseases of the heart, kidney, lung, coagulation disorder, immune deficiency, connective tissue disorder, diabetes, anemia, hemophilia, and malnutrition) Having a history of previous injury or surgery and visible lesions in the neck area

Design outcomes

Primary

MeasureTime frame
Scar spread. Timepoint: Scar spread will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on the observation of the researcher.;Erythema. Timepoint: Erythema will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on the observation of the researcher.;Dyspigmentation. Timepoint: Dyspigmentation will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on the observation of the researcher.;Track marks or suture marks. Timepoint: Track marks or suture marks will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on the observation of the researcher.;Hypertrophy/atrophy. Timepoint: Hypertrophy/atrophy will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on the observation of the researcher.;Overall impression. Timepoint: Overall impression will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on the observation of the researcher.;Pain. Timepoint: Pain will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on questions from the patient.;Itch. Timepoint: Itch will be measured at the beginning of the study and then weekly for 3 months. Method of measurement: Based on questions from the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Shahrokhi

Rasht University of Medical Sciences

shahrokhi.mail85@gmail.com+98 13 3336 9019

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026