Bipolar. Bipolar disorder
Conditions
Interventions
Intervention 1: Intervention group: 23 Patients in the intervention group will receive 3 mg melatonin tablets manufactured by Simorgh Daru Company in the form of 1 oral tablet 2 times a day from 24 ho
Sponsors
Gerash University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 18 years of age who are diagnosed with bipolar according to Diagnostic and Statistical Manual of Mental Disorders V (DSM-V) criteria and based on the diagnosis of a psychiatrist, and at the beginning of ECT treatment, refer to Rasht Shafa Hospital.
Exclusion criteria
Exclusion criteria: Schizophrenia Drug Abusers Psychiatric diseases with other mental illnesses Bradyarrhythmia Liver or kidney failure History of seizures Drug or alcohol use History of asthma or bronchospasm History of allergy to melatonin Pregnancy Breastfeeding Currently uncontrolled hypertension Active peptic ulcer Receiving nitroglycerin History of severe skin disease such as Steven Johnson.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary measurable outcome in this study is the evaluation of cognitive disorders caused by electroshock therapy in bipolar patients treated with melatonin by the Mini-Mental State Examination questionnaire, which is evaluated before and after 12 sessions of electroshock therapy. Timepoint: Before and after 12 sessions of electroshock therapy. Method of measurement: Mini-Mental State Examination questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| The examination of changes in systolic and diastolic blood pressure. Timepoint: Before and after each session. Method of measurement: The blood pressure of the patients are checked and measured by the doctor and the researcher every time the patient visits.;Check heart rate changes. Timepoint: Before and after each session. Method of measurement: The heart rate of the patients is checked and measured by the doctor and the researcher every time the patient visits.;Investigation of possible drug side effects. Timepoint: Before and after each session. Method of measurement: Patients are examined by doctors and researchers at each visit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Shahrokhi
Rasht University of Medical Sciences
Outcome results
None listed