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The effect of Nigella sativa chewing gum on generalized gingivitis

Clinical evaluation of Nigella sativa chewing gum on generalized gingivitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220516054874N21
Enrollment
80
Registered
2024-11-04
Start date
2024-11-05
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic gingivitis. Chronic gingivitis

Interventions

Intervention 1: Intervention group: Patients with generalized gingivitis chew black seed extract chewing gum (containing 5% black seed extract) twice a day (once in the morning after breakfast and onc

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with chronic generalized gingivitis Consent to admission to the study Having at least 18 natural teeth Having an average corrected gingival index of all teeth between 1.3 and 2.75 Having the average modified plaque index of all teeth at least 1.5

Exclusion criteria

Exclusion criteria: Smoking history Inability to attend follow-up meetings Patients receiving other systemic or local antibiotics

Design outcomes

Primary

MeasureTime frame
Plaque Index. Timepoint: The beginning of the study and 14 days later. Method of measurement: According to the PI index (0-10; 0 is without plaque, and 3 is the accumulation of a large amount of soft material in the gums, on the teeth, or at the edge of the gums).

Secondary

MeasureTime frame
Loe & Silness Gingival Index. Timepoint: The beginning of the study and 14 days later. Method of measurement: According to the Loe & Silness index (0-3; 0 is the normal gums and 3 is the severe inflammation).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Vafa Baradaran Rahimi

Mashhad University of Medical Sciences

baradaranrv@mums.ac.ir0095 5138012739

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026