The effect of Pentoxifylline on patients with coronary slow flow

Investigating the effect of Pentoxifylline on echocardiography parameters in patients with coronary slow flow

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220516054874N19

Enrollment

Registered

2024-08-03

Start date

2024-08-10

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary slow flow syndrome. Other forms of angina pectoris

Interventions

Intervention 1: Intervention group: Patients with slow coronary flow receiving common treatments (including aspirin, statins, beta-blockers and angiotensin-converting enzyme inhibitors) along with Pen

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosing slow flow of coronary arteries based on angiography results corrected TIMI frame count of more than 27 frames per second Age older than 18 years old Consent to admission to the study

Exclusion criteria

Exclusion criteria: Previous use of pentoxifylline or other methylxanthine drugs Renal dysfunction with GFR < 20 Hepatic dysfunction Body mass index < 18.5 Pregnant or suspected pregnancy

Design outcomes

Primary

Measure	Time frame
Echocardiographic parameters including: Left ventricular ejection fraction, Left Atrial Volume Index, E/e' ratio, diastolic velocities. Timepoint: The beginning of the study and one months later. Method of measurement: Echocardiography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Behzad Senobari

Mashhad University of Medical Sciences

senobarib4001@mums.ac.ir0095 5138012739

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026