The effect of the rose hip alcoholic extract on patients with heart failure

Investigating the effect of the rose hip alcoholic extract on echocardiographic parameters in patients with heart failure with reduced ejection fraction

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220516054874N18

Enrollment

Registered

2024-07-14

Start date

2024-07-22

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure. Heart failure

Interventions

Intervention 1: Intervention group: Taking rose hip alcoholic extract 250 mg tablets four times a day for one month along with standard treatment. Intervention 2: Control group: Taking placebo tablets

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age older than 18 years old Heart failure diagnosis with systolic dysfunction Signed written informed consent to participate in the study

Exclusion criteria

Exclusion criteria: New York Heart Association Class IV heart failure Renal dysfunction with GFR < 20 Hepatic dysfunction Body mass index < 18.5 kg/m2 Use of warfarin, lithium, chemotherapy drugs Pregnant or suspected pregnancy Other comorbidities including various infections, major surgery, type 1 diabetes, pituitary or adrenal insufficiency, cancer

Design outcomes

Primary

Measure	Time frame
Echocardiography parameters including LVEF? LVESVI? LVEDVI? LVIDs? LVIDd, LA volume index, LA strain, LV strain, PAP, RV diameter. Timepoint: The beginning of the study and one months later. Method of measurement: Echocardiography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Vafa Baradaran Rahimi

Mashhad University of Medical Sciences

baradaranrv@mums.ac.ir0095 5138012739

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026