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Evaluation of the effects of hawthorn extract on left ventricular ejection fraction in patients with Anterior ST segment elevation acute myocardial infarction treated with primary PCI

Evaluation of the effects of hawthorn extract (Crataegus monogyna) on left ventricular ejection fraction in patients with Anterior ST segment elevation acute myocardial infarction (Anterior STEMI) treated with primary PCI

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220516054874N12
Enrollment
60
Registered
2023-09-23
Start date
2023-10-07
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute anterior ST elevation Myocardial infarction treated with primary PCI. ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction

Interventions

Intervention 1: Intervention group: Patients with Anterior ST-segment elevation acute myocardial infarction treated with primary PCI receiving Crataegus monogyna extract tablet (400 mg, prepared by Di

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with Anterior ST-segment elevation acute myocardial infarction according to the American College of Heart criteria Consent to admission to the study Age more than 18 years old

Exclusion criteria

Exclusion criteria: Kidney failure under hemodialysis Severe liver failure with liver enzymes three times more than normal History of using medicinal products containing Crataegus monogyna extract History of heart disease and important valvular diseases in recent echocardiography

Design outcomes

Primary

MeasureTime frame
Left ventricle ejection fraction. Timepoint: At the beginning of the study and after 40 days of treatment. Method of measurement: Echocardioghraphy.

Secondary

MeasureTime frame
Changes in pulmonary artery pressure. Timepoint: At the beginning of the study and after 40 days of treatment. Method of measurement: Echocardioghraphy.;Left ventricular end-diastolic volume. Timepoint: At the beginning of the study and after 40 days of treatment. Method of measurement: Echocardioghraphy.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Vafa Baradaran Rahimi

Mashhad University of Medical Sciences

baradaranrv@mums.ac.ir0095 5138012739

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026