vasovagal syncope. Syncope and collapse
Conditions
Interventions
Intervention 1: Intervention group: Compression stockings with 25-30mm Hg pressure for one year. The group will have compression stockings with25-30 mm Hg pressure. All the participants' size for com
Sponsors
Tehran University of Medical Sciences
Right Arian Farmed
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with 18 = age = 65 years Vasovagal syncope as the cause of transient loss of conscious confirmed by Clinical diagnosis And Calgary syncope system score (CSSS) =-2 =2 episodes of VVS during the last year Capability of giving informed consent
Exclusion criteria
Exclusion criteria: Orthostatic hypotension (decrease in BP =20/10 mmHg after 5-minute stand test) Postural tachycardia (increase in heart rate =30 bpm after 5-minute stand test) Carotid sinus hypersensitivity (ventricular pause >3 or decrease in BP > 50 mmHG after carotid sinus massage, performed in patients 40 years or older) History of Seizure Currently using medications for treatment of vasovagal syncope Cardiac rhythm disorders including ventricular tachycardia, long QT syndrome, Brugada syndrome, arrhythmogenic right ventricular cardiomyopathy, complete heart block, or any conduction abnormality on ECG Severe valvular heart disease Hypertrophic cardiomyopathy Cardiac systolic dysfunction (ejection fraction =40%) Obstructive coronary artery disease Cardiac implantable electronic devices Prior recommendation of compression stocking by a health-care provider, or other indication for compression stocking use Foot ulcers and diabetic foot Chronic venous insufficiency Renal failure stage =3 (eGFR <60 mL/min/1.73 m2) Presence of a chronic severe illness Pregnancy, or intention to become pregnant in the next year Unwillingness to participate or to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of participants with recurrence of vasovagal syncope. Timepoint: Every three months until one year (three, six, nine, and twelve months after randomization). Method of measurement: Telephone follow-up questionnaire.;Time to first syncopal episode. Timepoint: Every three months until one year (three, six, nine, and twelve months after randomization). Method of measurement: Telephone follow-up questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of vasovagal syncopal episodes. Timepoint: Every three months until one year (three, six, nine, and twelve months after randomization). Method of measurement: Telephone follow-up questionnaire.;Time intervals between recurrent vasovagal syncope episodes during follow-up. Timepoint: Every three months until one year (three, six, nine, and twelve months after randomization). Method of measurement: Telephone follow-up questionnaire.;Incidence of any adverse effect after using compression stockings. Timepoint: Every three months until one year (three, six, nine, and twelve months after randomization). Method of measurement: Telephone follow-up questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMasih Tajdini
Tehran University of Medical Sciences
Outcome results
None listed