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comparison of curcuma with meloxicam in knee osteoarthritis pain relief

Evaluation of the efficacy of curcuma drug in comparison with meloxicam on pain relief and functional improvement of patients with knee osteoarthritis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220513054837N1
Enrollment
60
Registered
2022-09-03
Start date
2022-08-28
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis. Unspecified osteoarthritis, unspecified site

Interventions

Intervention 1: Intervention group: 1, Treatment in group 1 includes taking 15 mg of meloxicam orally daily for ten days and patients will be taught the method of correcting the way of life and Omepra

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: completing and signing a consent form having symptoms of knee osteoarthritis in at least one recent month age between 40 and 60 lack of the presence of any other disease around the affected limb

Exclusion criteria

Exclusion criteria: having diabetes having diseases such as Rheumatism, gout, collagen vascular and lupus having accompanying radiculopathy history of trauma, fracture and injury to the affected joint, nerve damage and neuropathies history of knee replacement on the affected side history of allergies to drugs used in the study history of significant heart, kidney, liver and lung disorders pregnant and lactating women BMI above 42 having brucellosis history of injection in the affected joint or in addition in the last 3 months inability to communicating and completing questionnaires patients taking anticoagulants cancer patients history or gastrointestinal disorders and stomach problems consuming warfarin and ticlopidine and aspirin uncontrolled hypertension very severe osteoarthritis of the knee based on radiology

Design outcomes

Primary

MeasureTime frame
Pain rate based on the score obtained from the Visual Analog Scale questionnaire in the study. Timepoint: before and after starting treatment in second , forth and fifth weeks. Method of measurement: Filling in the questionnaire VAS by the patient and reading the questionnaire information.;Knee disability based on the score obtained from the Oxford knee Scale in the study. Timepoint: before and after starting treatment in second , forth and fifth weeks. Method of measurement: Filling in the questionnaire OKS by the patient and reading the questionnaire information.;Morning stiffness based on the score obtained from the Western Ontario and McMaster Universities Arthritis Index in the study. Timepoint: before and after starting treatment in second , forth and fifth weeks. Method of measurement: Filling in the questionnaire WOMAC by the patient and reading the questionnaire information.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Reza Karimi

Shiraz University of Medical Sciences

dralirezakarimi1988@gmail.com+98 71 3720 9719

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026