Comparison of effect of Barij Anti-Fissure Cream with Lidocaine Ointment in Reducing the Severity of Anal Fissure in Children

The efficacy of herbal anti-fissure cream and Lidocaine Ointment in reducing the severity of hemorrhoids in children

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220512054829N4

Enrollment

Registered

2025-05-15

Start date

2025-05-15

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anal fissure. K60.2 Anal fissure, unspecified

Interventions

Intervention 1: Intervention group: Recipients of anti-fissure cream manufactured by Barij Essans Pharmaceutical Company along with Pidrolax syrup. Intervention 2: Control group: The recipients are 5%

Eligibility

Sex/Gender

All

Age

2 Years to 10 Years

Inclusion criteria

Inclusion criteria: Fischer's disease Age range 2 to 10 years

Exclusion criteria

Exclusion criteria: 1. Hemorrhoids 2. Anal fistula 3. Anal abscess 4. Malignant diseases 5. Food allergies 6. IBD diseases

Design outcomes

Primary

Measure	Time frame
Severity of bleeding. Timepoint: Days 0, 15, and 30 from the start of treatment. Method of measurement: Likert 4 options from 0 to 3.;Severity of pain. Timepoint: Days 0, 15 and 30 from the start of treatment. Method of measurement: Numerical score (NRS-11).;Grade of disease. Timepoint: Days 0, 15 and 30 from the start of treatment. Method of measurement: Grade 0: Healed, Grade 1: Fissure with internal anal sphincter evident. Grade 2: Deeper fissures with internal anal sphincter evident in a wider manner, Grade 3: Fissure of unknown depth, Grade 4: With perianal fistula.	—

Measure

Time frame

Severity of bleeding. Timepoint: Days 0, 15, and 30 from the start of treatment. Method of measurement: Likert 4 options from 0 to 3.;Severity of pain. Timepoint: Days 0, 15 and 30 from the start of treatment. Method of measurement: Numerical score (NRS-11).;Grade of disease. Timepoint: Days 0, 15 and 30 from the start of treatment. Method of measurement: Grade 0: Healed, Grade 1: Fissure with internal anal sphincter evident. Grade 2: Deeper fissures with internal anal sphincter evident in a wider manner, Grade 3: Fissure of unknown depth, Grade 4: With perianal fistula.

—

Secondary

Measure	Time frame
Side effects of drug used. Timepoint: On days 15 and 30 from the start of treatment. Method of measurement: Questioning the patient, clinical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Akbari

Kashan University of Medical Sciences

akbari1350_h@yahoo.com+98 31 5558 9396

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026