Skip to content

effect of Osteofix Barij cream® on knee osteoarthritis

Comparing the effect of Osteofix Barij cream® and Diclophenac ointment in patiants that affected to knee osteoarthritis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220512054829N3
Enrollment
80
Registered
2022-12-16
Start date
2022-08-11
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of knee. Unilateral primary osteoarthritis of knee

Interventions

Intervention 1: Intervention group: People use Osteofix cream made by Barij Essence pharmaceutical company twice a day when they have knee pain in a sufficient amount and topically for 28 days. This m

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: • Patients aged 40-80 years • The disease should be confirmed using the orthopedic specialist's tests. • Pain in at least one knee in the last month

Exclusion criteria

Exclusion criteria: • Patients who have a history of psychosomatic disorder. • Patients who were in the acute phase of knee arthritis or had secondary osteoarthritis (such as rheumatological diseases and severe joint trauma). • Suffering from osteoarticular diseases (rheumatoid arthritis, gout) • CHF functional class three or four New York Association class • Movement disorder due to a cause other than knee and hip OA. Having metabolic diseases at the same time and obesity (BMI=40) • Recorded allergy history, phenylketonuria • Pregnancy and breastfeeding patients • Sensory disorder in the lower limbs • Cause any skin sensitivity in case of drug use • Simultaneous drug treatments with forsamide, probenecid, anticoagulants, hydantotin, sulfonamides, lithium salts, methotrexate, beta blockers or muscle relaxants. • Arthritis caused by crystals •History of heart attack, intra-articular tumors, knee ligament instability in the last 12 months.

Design outcomes

Primary

MeasureTime frame
Pain level of patients with knee osteoarthritis based on WOMAC criteria. Timepoint: Before the start of intervention, day 14 of intervention, day 28 of intervention. Method of measurement: Womac questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Akbari

Kashan University of Medical Sciences

akbari1350_h@yahoo.com+98 31 5558 9057

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026