•" Investigating the Effect of Betamethasone Ophthalmic Ointment in Reducing the Recurrence of Polyposis After Frontal Sinus Surgery"

• Investigating the Results of Betamethasone Ophthalmic Ointment in Polypoid Frontal Sinus in Endoscopic Sinus Surgery and Its Effect in Reducing the Recurrence of Polyposis After Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220510054810N1

Enrollment

Registered

2023-05-21

Start date

2022-09-23

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polyp recurrence after sinus surgery.

Interventions

Intervention 1: Intervention group: 30 patients with bilateral frontal sinus polyps are selected according to the initial CT scan. Right or left sinus is randomly selected as intervention group. Betam

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Bilateral Polypoid Frontal sinus The size of the frontal sinuses should be approximately the same in each patient. No allergy to corticosteroides

Exclusion criteria

Exclusion criteria: Previous surgery of the frontal sinus Allergy to corticosteroides

Design outcomes

Primary

Measure	Time frame
Polyp recurrence. Timepoint: After surgery, two visits are performed, the first one after one and a half months and the second one after three months in order to check the endoscopic parameters including polyps/inflammation/discharges and CT scan indicators of the sinuses. Method of measurement: Using endoscopic examination and polyp, inflammation, discharge ( PID) criteria and sinus CT scan to measure soft tissue density ratio (STDR).	—

Measure

Time frame

Polyp recurrence. Timepoint: After surgery, two visits are performed, the first one after one and a half months and the second one after three months in order to check the endoscopic parameters including polyps/inflammation/discharges and CT scan indicators of the sinuses. Method of measurement: Using endoscopic examination and polyp, inflammation, discharge ( PID) criteria and sinus CT scan to measure soft tissue density ratio (STDR).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Emamgholizadeh

Iran University of Medical Sciences

info@iums.ac.ir+98 21 86701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026