Patients with poor ovarian response.
Conditions
Interventions
Intervention 1: Control group: A group of poor ovarian reserve women who undergo follicular puncture without any treatment. Intervention 2: Intervention group: A group of poor ovarian reserve women u
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
25 Years to 40 Years
Inclusion criteria
Inclusion criteria: previous IVF (In vitro fertilisation) that resulted in the recovery of less than three eggs or an abnormal ovarian reserve test involving less than five AFCs (Antral follicle count ) All women have a regular menstrual cycle. the level of follicles or AMH (Antimullerian Hormone) should be less than 1.1 ng / ml. those under 40 years of age.
Exclusion criteria
Exclusion criteria: Autoimmune disorders, sexually transmitted diseases, infectious diseases, infertility / tubal factor tube obstruction, chronic inflammatory diseases, endometriosis, chronic endometritis, and endocrine disorders such as thyroid dysfunction. anemia, thrombophilic disorders, current cancer diagnosis, or medical history of cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet-enriched plasma cell count. Timepoint: After plasma preparation. Method of measurement: With cell counting machine. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expression of folliculogenesis genes. Timepoint: After collecting granulosa cells on the day of oocyte someone both the control group and the treated group. Method of measurement: Real time PCR.;Hormone secretion levels. Timepoint: At monthly intervals after the puncture and before the puncture. Method of measurement: Immunoassay.;Antral follicle count. Timepoint: At monthly intervals after the puncture and before the puncture. Method of measurement: sonography.;The quality of oocytes. Timepoint: after puncture. Method of measurement: with stereomicroscope.;Oocyte and embryo quality. Timepoint: after puncture. Method of measurement: With a stereomicroscope.;Spontaneous fertility. Timepoint: 14 days after embryo transfer. Method of measurement: Pregnancy test and sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Asgari
Ghoum University of Medical Sciences
Outcome results
None listed