Comparing the effectiveness of mouthwashes containing betamethasone and dexamethasone in improving oral lichen planus

Comparison of the effectiveness of mouthwashs containing betamethasone with dexamethasone in the improvement of oral lichen planus lesions: A randomized double blind placebo controlled trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220509054789N2

Enrollment

Registered

2022-07-23

Start date

2022-07-23

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lichen planus. Lichen planus

Interventions

Intervention 1: Intervention group: 15 cc long-acting betamethasone (Kimia Drug Co.) in combination with 200 cc of AlMg stomach syrup, 3 times a day, 5 cc each time for 30 seconds, for 6 weeks. Patien

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with OLP who have not received treatment so far. Confirmation of OLP diagnosis by histological sampling Age above 18 years

Exclusion criteria

Exclusion criteria: Pregnancy Having uncontrolled diabetes Stomach ulcer Having high blood pressure Suffering from a systemic disease for which corticosteroid administration is contraindicated Age below 18 years Observation of dysplasia in histopathological view Get other treatments for OLP

Design outcomes

Primary

Measure	Time frame
Lesions size. Timepoint: Before and 6 weeks after the intervention. Method of measurement: Using the Thongprasom scoring system.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahar Khademnezhad

Tabriz University of Medical Sciences

khademnezhad@tbzmed.ac.ir+98 41 3333 6097

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026