Tolerance and complications of nutritional in patients admitted to the intensive care unit. Malabsorption due to intolerance, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group: The intervention group will receive 10 mg oral domperidone (1 mg in 1 ml), 10 ml Sterile water and 1000 mg acetaminophen oral solution. Intervention 2: Control grou
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Aged between 18 and 75 years No history of malabsorption disease (short bowel syndrome or Crohn's disease) Not having cirrhosis or abnormal liver function Not having burn injuries Having hemodynamic stability Not pregnant
Exclusion criteria
Exclusion criteria: Patients requiring vasopressor infusion Having study drugs allergies Coadministration of astemizole, terfenadine, cyclosporine, theophylline, warfarin, or a monoamine oxidase inhibitor Having gastrointestinal bleeding Having bowel obstruction Need for sedative therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric residual volume. Timepoint: Before and every three hours after intervention for 12 hours. Method of measurement: With using a 60 cc gavage syringe.;Intolerance. Timepoint: 12 hours after intervention. Method of measurement: Food intolerance test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Average blood pressure and heart rate. Timepoint: Before and 12 hours after intervention. Method of measurement: The monitor device.;Average heart rate. Timepoint: Before and 12 hours after intervention. Method of measurement: The monitor device.;Side effects of prokinetics. Timepoint: 12 hours after intervention. Method of measurement: ]ncluding cardiovascular disorders, bronchospasm, extrapyramidal symptoms, allergic reactions and pancreatic disorders. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBenyamin Fazli
Mashhad University of Medical Sciences
Outcome results
None listed