Survey the effect of zinc gluconate on asthma

Survey the effect of zinc gluconate supplementation on the serum levels of IL-35, oxidative stress, eosinophils and basophils status, spirometry test and clinical symptoms in patients with mild and moderate persistent allergic asthma.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220507054764N1

Enrollment

Registered

2022-11-02

Start date

2022-11-22

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

allergic asthma. J45.0

Interventions

Intervention 1: Intervention group:. Intervention 2: Control group:.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age 18 to 65 years Patients with mild to moderate persistent allergic asthma Body mass index(BMI):20-30 kg/m2 Both genders

Exclusion criteria

Exclusion criteria: smoking Pregnancy and lactation Cardiovascular diseases and other chronic diseases Use of antioxidant or zinc supplements in the last three months Not wanting to continue cooperation

Design outcomes

Primary

Measure	Time frame
IL-35. Timepoint: Before and two months after intervention. Method of measurement: ELISA.;TAC. Timepoint: Before and two months after intervention. Method of measurement: ELISA.;FEV1? FVC? FEV1/FVC. Timepoint: Before and two months after intervention. Method of measurement: According to the results of the spirometer-scale:percent.	—

Secondary

Measure	Time frame
Serum Zinc. Timepoint: Before and two months after intervention. Method of measurement: Serum Biochemistry Test/ Micro gr/ dl.;Clinical variables and the patient's general status. Timepoint: Before and two months after intervention. Method of measurement: according to the Questionnaires completed by physician superspecialty.;Complete blood cell count and differential count. Timepoint: Before and two months after intervention. Method of measurement: Based on laboratory measurement.	—

Measure

Time frame

Serum Zinc. Timepoint: Before and two months after intervention. Method of measurement: Serum Biochemistry Test/ Micro gr/ dl.;Clinical variables and the patient's general status. Timepoint: Before and two months after intervention. Method of measurement: according to the Questionnaires completed by physician superspecialty.;Complete blood cell count and differential count. Timepoint: Before and two months after intervention. Method of measurement: Based on laboratory measurement.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPardis Tofighzadeh

Ahvaz University of Medical Sciences

pardistofigh@gmail.com+98 61 3571 5794

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026