Post-appendectomy pain. Other acute postprocedural pain
Conditions
Interventions
Intervention 1: Intervention group: One hour before surgery, two 3 mg melatonin tablets (a total of 6 mg) manufactured by Vitans Nature, USA. Intervention 2: Control group: One hour before surgery, tw
Sponsors
Vice-Chancellery for Research Hormozgan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age of 18-80 years ASA class I & II Candidacy for appendectomy under general anesthesia
Exclusion criteria
Exclusion criteria: Addiction Allergy to melatonin Neurological or psychiatric disease History of taking analgesics for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-appendectomy pain. Timepoint: At 2, 12, and 24 hours after surgery. Method of measurement: Visual analogue scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of analgesics required. Timepoint: Up to 24 hours after surgery. Method of measurement: gr pethidine.;Sedation. Timepoint: At 2, 12, and 24 hours after surgery. Method of measurement: Ramsay Sedation Scale (RSS).;Side effects, including hypotension, bradycardia, and respiratory depression. Timepoint: Up to 24 hours after surgery. Method of measurement: Measurement of blood pressure (systolic blood pressure <90 mmHg), heart beat (<60), and respiratory rate (<12). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Abdollahzadeh Baghaei
Bandare-abbas University of Medical Sciences
Outcome results
None listed