Condition 1: Very Low Birth Weight. Condition 2: 1_2.499 weight. Condition 3: feeding intolerance. Condition 4: Abdominal distension. Condition 5: vomiting. Condition 6: Digestive bleeding. Condition 7: necrotic enterocolitis. Condition 8: Sepsis. Extremely low birth weight newborn Other low birth weight newborn Neonatal difficulty in feeding at breast P14 P11 P54.3 P77 P36.9
Conditions
Interventions
Intervention 1: Intervention group: early administration of oral probiotics in infants with very low birth weight. In this study, infants with very low birth weight from the first day of birth in the
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 2 Days
Inclusion criteria
Inclusion criteria: Hospitalization in NICU ward Born weight less than 1500 gr Stable hemodynamic status Ability to enteral nutrition Parent's written consent
Exclusion criteria
Exclusion criteria: Dissatisfaction of parents Impossibility of starting standard nutrition for neonate Existence of any congenital anomalies in neonate Neonate's CPR need in labor room Unstable clinical status Being a child of mothers with substance abuse disorders Severe abdominal distension or peptic hemorrhage Immunodeficiency in the family of neonate Congenital enteral perforation or atresia Complete forbidding of oral feeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feeding intolerance. Timepoint: In each feeding time. Method of measurement: Checklist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reach to born weight. Timepoint: Daily. Method of measurement: The weight of the infant will be assessed in terms of grams (in grams) until the clinical condition stabilizes and then daily until the day of discharge from the hospital. At the end of the weighting process, each premature infant will be assessed using Fenton growth charts. All measurements will be performed with a digital scale for fixed infants with the help of a researcher and will be recorded in a checklist created by the researcher.;Sepsis. Timepoint: Daily. Method of measurement: Based on having clinical and specific symptoms of sepsis (including irritability of the baby, rapid breathing or apnea, changes in the skin color of the baby, diarrhea, poor sucking, poor feeding) and positive result of blood culture and CRP result recorded in the checklist in daily evaluations.;Necrotic Enterocolitis. Timepoint: Daily. Method of measurement: Based on having clinical and specific symptoms of Necrotizing Enterocolitis (including lethargy, increased volume of food residue, bloody or bilious vomiting, ileus, persistent abdominal distension, bloody stools, symptoms of peritonitis and shock) and the Bells scale, which is evaluated in the checklist designed by the researcher.;Time of hospitalization. Timepoint: Daily. Method of measurement: Checklist.;Time to reach total nutrition. Timepoint: Daily. Method of measurement: The days required to reach enteral nutrition of 100 milliliter per kilogram per day are evaluated with the checklist made by the researcher. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Heydari
Shahid Beheshti University of Medical Sciences
Outcome results
None listed