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Effect of Elartrit in knee osteoarthritis

Evaluation of the efficacy of Elaeagnus angustifolia extract (Elartrit) drug in comparison with meloxicam on pain relief and functional improvement of patients with knee osteoarthritis referred to physical medicine and rehabilitation clinics of Shiraz University of Medical Sciences

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220502054724N1
Enrollment
60
Registered
2022-07-11
Start date
2022-07-23
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. Osteoarthritis of knee, unspecified

Interventions

Intervention 1: Control group: Treatment in this group includes taking 15 mg of meloxicam daily for 15 days, as well as educating patients in the clinic on lifestyle modifications and exercises suitab

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Filling and signing the consent form Having pain and other clinical manifestations of knee osteoarthritis in the last month Being between 40 to 60 years old Not having any periarticular disease around the joint in question

Exclusion criteria

Exclusion criteria: High grade arthritis according to radiology Presence of diabetes mellitus Presence of rheumatologic and collagen vascular diseases such as gout and lupus Presence of concomitant radiculopathy Presence of neural damage and neuropathy Presence of brucellosis Presence of any malignancy Presence of a history of significant liver disease Presence of a history of significant liver disease Presence of a history of significant kidney disease Presence of a history of significant cardiac disease Presence of a history of significant pulmonary disease A body mass index greater than 42 Presence of a history of knee joint replacement in the knee being studied Presence of a history of trauma or fracture in the knee being studied Presence of bleeding disorders Presence of an inability to communicate and to complete questionnaires Presence of a history of allergic or hypersensitivity reaction to the drugs being used Presence of a history of injections in the last 3 months within or around the joint being studied Presence of a state of pregnancy or lactation Patients taking anticoagulant medications Presence of a history of gastrointestinal and stomach disease Use of warfarin and ticlopidine

Design outcomes

Primary

MeasureTime frame
Pain caused by knee osteoarthritis. Timepoint: Before starting the intervention; 2, 4, and 8 weeks later. Method of measurement: Visual analog scale; Western Ontario and McMaster Universities Arthritis Index; Oxford knee scale; Patient satisfaction.

Secondary

MeasureTime frame
Degree of knee dysfunction. Timepoint: Before starting the intervention; 2, 4, and 8 weeks later. Method of measurement: Western Ontario and McMaster Universities Arthritis Index; Oxford knee scale; Patient satisfaction.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Haghighat

Shiraz University of Medical Sciences

mammadht@gmail.com+98 71 3626 1467

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026