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Metoclopramide versus ondansetron for preventing nausea and vomiting after cesarean section

Comparing the effect of Metoclopramide and ondansetron for preventing nausea and vomiting after cesarean section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220502054722N1
Enrollment
150
Registered
2022-11-26
Start date
2022-08-22
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative nausea and vomiting. Nausea with vomiting, unspecified

Interventions

Intervention 1: Intervention group 1: 5 minutes before spinal anesthesia, intravenous metoclopramide 10 mg/2 ml (DarouPakhsh Co., Iran) diluted with 8 ml normal saline will be injected within 2 minute

Sponsors

Vice-Chancellery for Research, Hormozgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age of 18-40 years old ASA class I and II Term and singleton pregnancy Candidacy for elective cesarean section

Exclusion criteria

Exclusion criteria: Contraindications of spinal anesthesia History of postoperative nausea and vomiting History of severe motion sickness Gestational hypertension History of opioid abuse Preeclampsia History of taking antiemetics one week before surgery Less than six hours fasting before surgery Emergency cesarean section

Design outcomes

Primary

MeasureTime frame
Postoperative nausea and vomiting. Timepoint: At 1, 2, 4, and 6 hours after surgery. Method of measurement: Number of episodes and severity using a visual analog scale.

Secondary

MeasureTime frame
Hypotension. Timepoint: Before surgery and at 1, 2, 4, and 6 hours after surgery. Method of measurement: Using a standard sphygmomanometer.;Diastolic blood pressure. Timepoint: Before surgery and at 1, 2, 4, and 6 hours after surgery. Method of measurement: Using a standard sphygmomanometer.;Heart rate. Timepoint: Before surgery and at 1, 2, 4, and 6 hours after surgery. Method of measurement: Counting the heart beat per minute.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHasan Movahedi

Bandare-abbas University of Medical Sciences

20goodlife2020@gmail.com+98 76 3334 7000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026