study of the effect of drug treatment (OCP and Methergine) in patients with pregnancy remnants

Comparative study of drug treatment outcomes (OCP and Methergine) in aborted patients with pregnancy remnants

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220430054708N1

Enrollment

Registered

2022-05-31

Start date

2022-06-14

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Placental remnants. Incomplete spontaneous abortion without complication

Interventions

Intervention 1: The first intervention group will receive OCP (0.03 mg Ethinylestradiol and 0.15 Desogestrel) daily for 21 days. In addition, 100 mg oral Doxycycline capsules every 12 hours for 10 day

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Forgotten abortion under 20 weeks Hemoglobin above 10 No contraindications to receiving Methergine or OCP Stability of the patient's vital signs at the beginning of the treatment

Exclusion criteria

Exclusion criteria: Active liver disease Cardiovascular disease HTN infection Advanced neurological disease Symptoms of infection Severe bleeding

Design outcomes

Primary

Measure	Time frame
Incidence of infection. Timepoint: At the beginning of the study and one month after the start of the study. Method of measurement: Based on the clinical signs, the fever is mostly equal to 38 degrees Celsius.;Gastrointestinal symptoms. Timepoint: At the beginning of the study and one month after the start of the study. Method of measurement: visual analogue scale.;Cardiovascular complications. Timepoint: At the beginning of the study and one month after the start of the study. Method of measurement: Clinical signs.	—

Measure

Time frame

Incidence of infection. Timepoint: At the beginning of the study and one month after the start of the study. Method of measurement: Based on the clinical signs, the fever is mostly equal to 38 degrees Celsius.;Gastrointestinal symptoms. Timepoint: At the beginning of the study and one month after the start of the study. Method of measurement: visual analogue scale.;Cardiovascular complications. Timepoint: At the beginning of the study and one month after the start of the study. Method of measurement: Clinical signs.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Rafiei

Esfahan University of Medical Sciences

samira.rafiee@ymail.com+98 31 3792 3071

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026